[Immunoblot as a supplemental test to detect antibodies to hepatitis C virus in blood donors].
نویسندگان
چکیده
Supplemental tests using Immunoblot are recommended to improve specificity of anti-HCV by ELISA. In Brazil immunoblot is not officially recommended. Aiming to identify EIA false-positive rate 70 positive EIA anti-HCV blood donors were submitted to 3rd generation immunoblot at Hemocentro of Mato Grosso State where polymerase chain reaction tests are not performed. There were 44 (62.9%) immunoblot-positive, 22 (31.4%) negative and 4 (5.7%) indeterminate. Anti-HCV immunoblot can distinguish blood donors with false-positive ELISA from those who need medical assessment. Our data suggest that immunoblot could be useful in Brazilian blood banks where molecular biology tests are not available.
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ورودعنوان ژورنال:
- Revista da Sociedade Brasileira de Medicina Tropical
دوره 35 1 شماره
صفحات -
تاریخ انتشار 2002